Five Year Retrospective

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UCI, UCLA awarded $8 million to launch collaborative stem cell clinic

In a first-of-its-kind alliance, UC Irvine and UCLA have received a five-year, $8 million grant from the California Institute of Regenerative Medicine to establish a CIRM Alpha Stem Cell Clinic.

Daniela Bota, M.D., Ph.D. Named Clinic Director

October 2017

Dr. Daniela A. Bota is a UCI Health neuro-oncologist who specializes in the treatment of primary and metastatic brain and spinal cord tumors, as well as in the neurological complications of cancers.

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Leonid Groysman M.D., Named ASCC Assistant Clinical Director

April 2019

Dr. Leonid Groysman is a specialist in Neurocritical Care.

UCI-led team begins first clinical trial of stem cell-based retinitis pigmentosa treatment

Participants are sought for safety study on the use of retinal progenitors in the eye.

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UCI opens new stem cell clinical trial for ALS patients

The University of California, Irvine Alpha Stem Cell Clinic and the UCI Department of Neurology will be conducting a randomized Phase 3 trial.

Dr. Bota's Clinical Trial for Glioblastoma Presents Measurable Success

Amanda Johnson, a glioblastoma patient, had her tumor shrunk so small that it is no longer measurable thanks to promising clinical trials lead by Dr. Daniela Bota.

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UCI researchers investigate use of stem cells to improve recovery of stroke survivors

PISCES III is a phase IIb clinical trial in the U.S. for stroke survivors living with chronic disability.

UCI stem cell researcher receives $4.8 million CIRM grant to address traumatic brain injury

Brian Cummings receives the only grant to support traumatic brain injury program funded by CIRM.

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UCI stem cell researcher receives CIRM funding for stem cell-based retina therapy to treat blindness

Grant will fund continued development of a stem cell-based therapy for a vision-robbing eye disease, retinitis pigmentosa.

Leslie Thompson gets $6 million CIRM grant to advance Huntington’s disease treatments

A Chancellor’s Professor of psychiatry & human behavior and neurobiology & behavior, Leslie Thompson has received nearly $12 million from CIRM since 2008 supporting her efforts to slow down progression of Huntington’s disease.

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Conferences and Meetings

December 2014 – UCI hosted CIRM ASCC network launch meeting

April 2019 – UCI’s ASCC director Dr. Daniela Bota co-organized CIRM’s Brainstorming Neurodegeneration Ideation Workshop

September 2019 – UCI School of Medicine hosted CIRM President and CEO Dr. Maria Millan for the inaugural Dean’s Distinguished Lecture Series

Encouraging community access

UCI Sue & Bill Gross Stem Cell Research Center seeks to demystify its work with public lecture series, open houses.

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Future Focus

Recent major gifts to UCI SCRC will help to support clinic activities for many years

  • Cullen gift of $2.8 million
  • Holland gift of $1.6 million

Major projects in development at UCI SCRC

  • Establishing a 4-bed infusion center to conduct in-patient visits for early phase trials
  • Establishing a GMP production facility for clinical-grade stem cell-derived therapeutics