Daniela A. Bota, M.D., Ph.D. Senior Associate Dean for Clinical Research Chief Scientific Officer, UCI Center for Clinical Research Medical Director, Comprehensive Brain Tumor Program University of California, Irvine 101 The City Drive South, Bldg. 23 Orange, CA 92868 Phone: 714-456-8000 Email: dbota@uci.edu
- Dr. Bota is the senior associate dean of clinical research in the School of Medicine and medical director of Neuro-Oncology at the University of California in Irvine.
- Dr. Bota’s research is focused on translational research in malignant gliomas. Her clinical interests include the comprehensive treatment of brain tumor patients. She currently serves as a principal investigator for multiple studies including novel chemotherapy agents (marizomib), cellular immunotherapy studies (ERC1671 and AV-GBM-1), and a phase 2 study of Optune in Anaplastic Astrocytoma. Her articles have been published in journals such as Cancer Research, Neurological Oncology, Cancer, CNS Oncology, and the Journal of Neuro-Oncology.
Section 2
Jefferson W. Chen, M.D., Ph.D., FACS Clinical Professor Director of NeuroTrauma Director of Neurosurgical Critical Care Fellowship Department of Neurological Surgery University of California, Irvine 101 The City Drive South, Pavilion 1, Bldg. 30 Orange, CA 92868 Phone: 714-456-6966 Email: jeffewc1@hs.uci.edu
- Dr. Chen is a neurosurgeon who is board certified in neurosurgery, neurocritical care and neuro-oncology. He is affiliated with numerous hospitals, including UCI Medical Center and more.
- His clinical interests include traumatic brain injury, normal pressure hydrocephalus, stroke and brain tumor.
- He is a leader in techniques such as multimodal brain monitoring for traumatic brain injury and the use of brain path technology to access deep-seated lesions.
Section 3
Farshid Dayyani, M.D., Ph.D. Associate Clinical Professor Chao Family Comprehensive Cancer Center UCI School of Medicine UC Irvine Health 101 The City Dr. South Orange, CA 92868 Phone: 714-456-8161 Email: fdayyani@uci.edu
- Associate professor at Division of Hematology/Oncology, Department of Medicine, UC Irvine School of Medicine
- Dr. Dayyani is a board-certified UCI Health medical oncologist at the UCI Health Chao Family Comprehensive Cancer Center and the adjacent UCI Health H.H. Chao Comprehensive Digestive Disease Center.
- Dr. Dayyani’s goal is to bring cutting edge treatments to patients with gastrointestinal cancers through innovative clinical trials.
Research interests include clinical research, translational research, colorectal carcinomas, gastrointestinal malignancies.
Section 4
Leonid I. Groysman, M.D. Associate Clinical Professor Neurocritical Care Fellowship Director Departments of Neurology and Neurological Surgery University of California, Irvine 101 The City Drive South, Pavilion 1, Bldg. 30 Orange, CA 92868 Phone: 714-456-7720 Email: lgroysma@uci.edu
- Health neurologist and assistant clinical professor at the Department of Neurology, UCI School of Medicine.
- Specialties include neurocritical care and neurology.
- Director of stroke studies for the Alpha Stem Cell Clinics (ASCC) and assistant clinical director for the Stem Cell Research Center (SCRC).
- Dr. Groysman has been principal investigator and UCI site leader on multiple investigator-initiated and industry-sponsored clinical trials, focused specifically on surgical implantation of stem cell therapeutics in subjects with recent ischemic stroke.
- He has been involved in many clinical trials. Out of many, stem cell research is one of them. Stem Cell Clinic provides the necessary infrastructure, and medical and operational expertise to effectively and efficiently drive novel stem cell therapies to clinical trials and ultimately change clinical practice.
Section 5
Hirohito Ichii, M.D. Professor Pancreas/Islet Transplant Program Director, Division of Transplantation Department of Surgery University of California, Irvine 333 City Boulevard West Suite 1205, Orange CA 92868 Phone: 714-456-8590 Email: hichii@uci.edu
- Associate professor, Division of Transplantation, Department of Surgery, UCI School of Medicine
- Specialties include transplant surgery and general surgery
Xiao-Tang Kong, M.D., Ph.D. Associate Clinical Professor Clinical Director, Neuro-Oncology Program Department of Neurology UC Irvine School of Medicine 200S. Manchester Ave, Suite 206 Orange, CA 92868 Phone: 714-456-7214 Email: xkong@uci.edu
- Dr. Kong is a board-certified UCI Health Neuro-Oncology specialist in the diagnosis and management of primary brain tumor, CNS lymphoma, and metastatic cancers of the brain and spinal cord, as well as managing neurological complications from cancers and their therapies.
- She is also a neuro-oncology hospitalist who ensures continuity of care for patients during their hospitalization.
- Dr. Kong is deeply involved in managing clinical trials for brain and spinal cord tumors
Section 7
Nimisha K. Parekh, MD, MPH, FACG, AGAF Associate Professor, Department of Medicine, Division of Gastroenterology & Hepatology UC Irvine Health University of California Irvine 101 The City Drive, City Tower, Suite 400, Zot 4092 Irvine, CA 92868 Phone: 714-456-6745 Clinical Line: 714-456-7358 Email: parekhn@hs.uci.edu
- Dr. Nimisha K. Parekh, a board-certified UCI Health internist and gastroenterologist, is director of the UCI Health Inflammatory Bowel Disease (IBD) Program. She believes in an integrated approach to managing inflammatory bowel disease (IBD).
- Her research interests include outcomes in Crohn’s disease and ulcerative colitis, clinical trials for new drug therapies to treat IBD, women’s issues and the role of ethnicity in disease outcomes.
- Parekh serves as co-director of the Crohn's and Colitis Foundation of America-Orange County Chapter.
Section 8
Nicolás Phielipp, M.D. Assistant Professor, Department of Neurology UC Irvine Health University of California Irvine 1 Medical Plaza Dr., Suite 1323 Irvine, CA 92697 Phone: 949-824-8600 Email: nphielip@uci.edu
- Dr. Phielipp is an assistant professor in the neurology department at UC Irvine Health.
- Research interests include the management of Parkinson's disease and task-specific dystonias such as writer's cramp and musician's, golfer's or tennis player's dystonia. He is also interested in developing techniques to better diagnose Parkinson's disease, understanding the mechanisms involved in deep brain stimulation, and improving the diagnosis and management of movement disorders in general.
- Participated in several research projects involving transcranial magnetic stimulation for the treatment of mood and motor symptoms of Parkinson's disease, the mechanism of deep brain stimulation in cervical dystonia, the mechanism of action of botulinum toxin in the treatment of writer's cramp and musician's dystonia and the treatment of psychogenic/functional tremor
Section 9
Qin Yang, M.D., P.h.D. Associate Professor of Medicine, Physiology and BiophysicsDirector, UC Irvine Diabetes Center Interim Chief, Division of Endocrinology, Diabetes and Metabolism UC Irvine Diabetes Center University of California, Irvine 101 The City Drive South, Pavilion 1, Bldg. 30 Orange, CA 92868 Phone: 714-456-7720 Email: qin.yang@uci.edu
- Dr. Yang is an assistant professor in the Physiology & Biophysics department at UCI.
- His research interest includes epigenetic regulation of insulin resistance and energy expenditure in obesity and type 2 diabetes.
- The research in his laboratory focuses on identifying novel targets and developing new tools for the treatment of obesity and diabetes. He is particularly interested in understanding epigenetic regulation of energy expenditure and insulin resistance. Dr. Yang's laboratory has developed several animal models to ask questions regarding how epigenetic signatures are altered in obesity and type 2 diabetes, and how the altered epigenetic signatures regulate insulin sensitivity and energy metabolism. Another direction of the laboratory is directly related to transnational medicine. They are developing new tools for drug delivery to metabolic organs such as fat tissue and liver. The goal is to increase metabolic rate selectively in these organs for treating obesity and diabetes.
